Dragons A, who have five points after the first three games of the competition, will once again be captained by back row Lennon Greggains.
Prop Josh Reynolds comes into the front row while Max Williams is called up to partner Screech in the second row.
Ben Fry is named at blindside flanker in the final change to the pack.
Scrum half Rhodri Davies will start the game – joining forces with Ben Botica at half back – while George Gasson is named on the wing.
The final change sees Tom Hoppe come in at centre to play alongside James Benjamin.
Joe Davies, Rob Brookson and Will Kelly are named among the replacements.
Score updates from the clash at Ballymena RFC will appear on our social channels on Saturday afternoon.